【作者】 Zhao Fei-yi (赵非一)1, Zhang Zhe-yuan (张浙元)2, Xia Xiao-jie (夏小芥)3, Hong Yu-Fang (洪钰芳)

【机构】 本站原创

【摘要】

Objective: To investigate the effectiveness and safety of manual acupuncture for memory loss and sleep quality in chronic insomniacs.

Methods: A total of 60 eligible participants were enrolled and randomized into either a treatment group or a control group, with 30 cases in each group. The treatment group was intervened by manual acupuncture whereas the control group was given sham acupuncture. In the two groups, the interventions were offered once every other day and three times a week, for 8 weeks in total. Before and after the treatment, Pittsburgh sleep quality index (PSQI) and event- related potentials (ERPs) were used to assess the patients’ sleep quality and memory, respectively. Meanwhile, adverse events were monitored and recorded.

Results: After 8-week treatment, both the treatment group and the control group showed a significant decrease in the PSQI global score (P<0.001, P<0.01), and the decrease in the treatment group was more significant than that in the control group (P<0.001). The intra-group comparisons of ERPs indicated that, the latencies of N1 and P3 were shortened and the amplitudes of N1 and P3 were increased in the treatment group after the intervention, and the differences were statistically significant (P<0.05, P<0.001); in the control group, there were no significant changes in the latency and amplitude after the treatment (P>0.05). The between-group comparisons of ERPs showed that the treatment group was more effective than the control group in shortening the latency of P3 (P<0.01).

Conclusion: Acupuncture can be a safe and effective treatment option for chronic insomnia coupled with memory impairment.